Significance of Alignment Positions
نویسنده
چکیده
منابع مشابه
A Novel Genetic classification of SARS coronavirus-2 following whole nucleic acid and protein alignment of the isolated viruses
Background and aims: The end of 2019 has marked the year, which the human population encountered a novel virus; SARS-CoV-2 that causes a disease namely COVID-19. Here we focused on the genome and protein mutations and subsequently suggested a new classification of the SARS-CoV-2. Materials and Methods: Our study showed that some extra positions in the virus genome play a key role in the SARS-C...
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G protein-coupled receptors (GPCRs) are a superfamily of seven transmembrane-spanning proteins involved in a wide array of physiological functions and are the most common targets of pharmaceuticals. This study aims to identify a cohort or clique of positions that share high mutual information. Using a multiple sequence alignment of the transmembrane (TM) domains, we calculated the mutual inform...
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Background: Knee malalignment is an important modifiable cause of osteoarthritis (OA). Surgical therapeutic procedures depend on proper knee alignment assessment. The purpose of this study was to compare knee alignment parameters between double and single leg weight-bearing radiographs and to evaluate the reproducibility of inter- and intra-observer measurements. Methods: One hundred eight p...
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It is a standard procedure to compare new amino acid sequences to databases of proteins that have been studied already in order to find similarities in structure and function. This comparison can be sequence–sequence or sequence– structure based. In order to compare, an alignment is performed of the target protein sequence (whose structure we are searching) with a template protein (whose struct...
متن کاملبررسی اثر قرار گرفتن مادر در وضعیت های انتخابی خود بر طول بخش فعال مرحله اول زایمان
Background and Purpose: Left to their own choice, parturients will usually select positions they find most comfortable and will frequently change their positions over the course of labor. Maternal changing the positions will adjust fetus alignment to pass through the birth canal. Therefore, maternal positioning choice will include those positions with maximum comfort and those which improve the...
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